Antacids, especially aluminum-containing antacids may delay and decrease absorption and serum concentrations of orally administered isoniazid; concurrent use should be avoided, or patients should be advised to take oral isoniazid at least 1 hour before aluminum-containing antacids .

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the two regimens likely have similar side effect profiles 15 , 26 , but four months of rifampin does not require dot and is less expensive than three months of isoniazid and rifapentine.

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yet sizemore doesn t anticipate an end to isoniazid s role in tb therapy for people who have drug-sensitive tb, to get isoniazid is often a life-saving action.


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