Insulin dosage or timing of dosage may require adjustment because the action of metoclopramide will hasten the movement of food to the intestines and therefore the rate of absorption.

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however, the doses especially the ed50s of metoclopramide used in the present study are close to its antiemetic ones 10, 20 and 40 mg kg, body weight, orally used in pigeons treated with reserpine 9 .

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14 18 the first found no significant differences between metoclopramide and sumatriptan in the rate of complete resolution of migraine 2.

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