The safety and efficacy of tamoxifen for girls aged 2 to 10 years with mccune-albright syndrome and precocious puberty have not been studied beyond one year of treatment.

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recent studies have shown that the antiestrogens tamoxifen and raloxifene may protect against breast cancer, presumably because of a blockade of estrogen receptor er -mediated transcription.

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researchers are investigating whether women on tamoxifen should receive annual vaginal ultrasound exams to screen for endometrial thickening.

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