A between-group comparison for 6- to 8-week placebo-controlled trials revealed no statistically significant risperdal placebo differences in the proportions of patients experiencing potentially important changes in routine serum chemistry, hematology, or urinalysis parameters.

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several early bellwether risperdal trials have resulted substantial damage awards after juries evaluated the evidence, including one verdict of 70 million awarded to the family of a five year old boy who developed breasts following use of the medication.

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the jury found that janssen failed to properly warn about the ability of risperdal to cause gynecomastia.

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at the initiation of therapy with carbamazepine or other known cyp 3a4 hepatic enzyme inducers, patients should be closely monitored during the first 4-8 weeks, since the dose of risperdal consta may need to be adjusted.

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in 2010, investors became so angry over the risperdal controversies that they filed a derivative lawsuit against the johnson johnson s executives in new jersey federal court.


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