While adjusting the dosage of zyloprim allopurinol in patients who are being treated with colchicine and or anti-inflammatory agents, it is wise to continue the latter therapy until serum uric acid has been normalized and there has been freedom from acute gouty attacks for several months.

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by inhibiting uric acid synthesis, allopurinol decreases its excretion.

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rashes that develop in reaction to allopurinol treatment can vary from a slight skin irritation to a severe allergic reaction.


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