On average, people with fibromyalgia who took amitriptyline reported that their pain improved by almost two points on a 10-point scale compared to those who took a placebo.

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they imply that if i, as a psychiatrist, treat a patient with some unspecified kind of depressive condition possibly varying from mild sub-clinical symptoms to severe psychotic depression i am unlikely to see much extra effectiveness by choosing amitriptyline over another antidepressant, even an ssri.

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