To address if serpina2 was accumulating in the er, we carried out double-labeling assays against the v5-tag and two er markers, calnexin canx or protein disulfide-isomerase a3 pdia3 .

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hi some embodiments, the serpina-1 polypeptide comprises the amino acid sequence set forth as m 0x ieqntksplfmgkwnptqk seq id no 2 .

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in some embodiments, the serpina-1 polypeptide comprises the amino acid sequence set forth as m ox ieqntksplfm ox gkwnptqk seq id no 3 .

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